Scientists Find a New Approach to Treat Prostate Cancer

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Scientists Find a New Approach to Treat Prostate Cancer Apr 6th 2013, 15:24 The finding, which also describes a molecular chain of events that controls cell growth and metastasis, could lead to novel ways to control disease progression. Working in close collaboration, the labs of Maria T. Diaz-Meco, Ph.D., and Jorge Moscat, Ph.D., found that PKCζ controls the activation of a pro-tumor gene called c-Myc. Normally, PKCζ's alteration keeps c-Myc in check. But PKCζ levels are low in prostate and other cancers, leaving c-Myc free to enhance cell growth and metastasis. This study, published April 1 in the Proceedings of the National Academy of Sciences, suggests that restoring PKCζ could provide a new approach to treating prostate cancer. Source-Eurekalert

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