The researchers, led by Dr Cristina Tufarelli, in the School of Graduate Entry Medicine and Health Sciences, discovered that the presence of this faulty genetic element - known as chimeric transcript LCT13 - is associated with the switching off of a known tumour suppressor gene (known as TFPI-2) whose expression is required to prevent cancer invasion and metastasis.
Their findings suggest that LCT13 may be involved in switching off TFPI-2.
The study has been published in the journal Nucleic Acid Research.
Source-ANI
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